Physiotherapy & Electrotherapy Equipment | Balego

Ionto4™ Iontophoresis Electrodes | Drug-Delivery Electrode Treatment Kits, 12/Box

Ionto4™ Iontophoresis Electrodes | Drug-Delivery Electrode Treatment Kits, - Main image
$73.2 $150 In stock

Category: Iontophoresis

The Ionto4™ Iontophoretic Delivery Kit is a single-use drug-delivery electrode system for professional iontophoresis treatments with FDA-cleared constant-current iontophoresis devices. Available from Balego, Ionto4™ kits combine an active drug electrode, a return/ground electrode, and an alcohol prep pad in individually packaged treatment kits.

Each Ionto4™ electrode is designed with carbon-Ag/AgCl technology, an absorbent drug matrix, a large adhesive surface area, and medical-grade materials not made with natural rubber latex. The collection is available in three square sizes plus a butterfly shape, giving clinicians flexibility when selecting drug reservoir volume, treatment-area fit, and electrode footprint.


Product Overview

Ionto4™ is a drug-delivery iontophoresis electrode treatment kit intended for administering soluble salts or other medications into the body for medical purposes as an alternative to hypodermic injection when used under proper professional direction.

Each box includes 12 individual treatment kits. Each treatment pouch contains:

Included Item Purpose
One active drug electrode Holds the medication or solution for iontophoresis delivery
One return / ground electrode Completes the treatment circuit and supports patient comfort
One alcohol prep pad Used to clean the skin before electrode placement

The system is designed for use with FDA-cleared, constant-current iontophoresis devices. Medication is not included.


Why Choose Ionto4™ Iontophoresis Electrodes?

Single-Use Treatment Kits

Each pouch contains the components needed for one treatment setup: active electrode, ground electrode, and alcohol wipe. Single-use packaging supports clean, organized treatment-room workflow.

Carbon-Ag/AgCl Technology

Ionto4™ electrodes use carbon-Ag/AgCl, or carbon silver/silver chloride, technology designed for maximum strength and precise buffering during iontophoresis treatment.

Highly Absorbent Drug Matrix

The active electrode includes a highly absorbent matrix designed to hold the drug or solution evenly after proper hydration.

Large Adhesive Surface Area

Each electrode has a large adhesive surface area to help support secure placement during treatment.

Comfort-Focused Ground Electrode

The large ground electrode surface area is designed to lower sensation and increase patient comfort during use.

Multiple Shapes and Fill Volumes

Choose from Small, Medium, Large, and Butterfly options depending on fill volume, placement area, and clinical workflow.

Not Made With Natural Rubber Latex

Both electrodes are not manufactured with natural rubber latex and are made with biocompatible materials.

Order from Balego

Buy Ionto4™ iontophoresis electrodes from Balego for professional therapy product sourcing, free USA shipping, and Balego’s best-price guarantee.


Size and SKU Comparison

SKU Size / Shape Size Label Drug Matrix Fill Volume Best For
NC89375 Small Square Small Square 2.75" 1.5cc Smaller treatment areas or lower fill-volume needs
NC89376 Medium Square Medium Square 3.25" 2.5cc General-purpose iontophoresis workflows
NC89377 Large Square Large Square 3.5" 4.0 cc Larger drug matrix volume and broader placement area
NC89378 Butterfly Butterfly 3.75" × 3.3" 2.0 cc Contoured placement areas where butterfly shape may fit better

Best Ionto4™ Option by Clinical Need

Clinical Need Recommended Option SKU Why It Fits
Smallest drug matrix volume Small Square NC89375 1.5cc fill volume for smaller applications
Balanced everyday option Medium Square NC89376 2.5cc fill volume for general treatment setups
Largest reservoir volume Large Square NC89377 4.0 cc fill volume for larger matrix capacity
Contoured fit Butterfly NC89378 A 2.0 cc butterfly shape can help with placement around certain areas
Three square size choices Small, Medium, or Large NC89375–NC89377 Lets clinicians choose by surface area and drug matrix volume
Non-square layout Butterfly NC89378 Useful when a traditional square electrode is not the preferred fit

Product Comparison: Small vs. Medium vs. Large vs. Butterfly

Feature Small Square Medium Square Large Square Butterfly
SKU NC89375 NC89376 NC89377 NC89378
Fill volume 1.5cc 2.5cc 4.0 cc 2.0 cc
Shape Square Square Square Butterfly
Size 2.75" 3.25" 3.5" 3.75" × 3.3"
Box quantity 12 kits 12 kits 12 kits 12 kits
Active electrode included Yes Yes Yes Yes
Ground / return electrode included Yes Yes Yes Yes
Alcohol prep pad included Yes Yes Yes Yes
Best use case Smaller placement needs General-purpose use Larger reservoir needs Contoured placement needs

How to Choose the Right Ionto4™ Size

Choose Small Square, NC89375, if:

  • You need the smallest listed drug matrix volume.

  • You want a compact square electrode.

  • The treatment area is smaller.

  • A 1.5cc fill volume is appropriate for the clinical plan.

Choose Medium Square, NC89376, if:

  • You want a balanced general-purpose option.

  • You need more fill volume than Small but less than Large.

  • A 2.5cc fill volume matches the treatment plan.

  • Your clinic wants a versatile square electrode option.

Choose Large Square, NC89377, if

  • You need the largest listed drug matrix volume.

  • You prefer a broader square footprint.

  • A 4.0cc fill volume is appropriate.

  • The treatment area and device setup allow for a larger electrode.

Choose Butterfly, NC89378, if:

  • You want a non-square shape.

  • A 2.0cc fill volume is appropriate.

  • The placement area may benefit from a contoured butterfly design.

  • A square electrode is not the best fit for the selected site.


Ionto4™ Technology and Material Features

Feature Description Benefit
Carbon-Ag/AgCl technology Carbon silver/silver chloride electrode design Supports precise buffering and consistent iontophoresis performance
Highly absorbent drug matrix An active electrode matrix holds medication or solution Helps distribute the drug or solution across the matrix after proper hydration
Large adhesive area Broad surface adhesion area Helps maintain contact during treatment
Large ground electrode The return electrode has a larger surface area Helps lower sensation and improve comfort
Hypoallergenic materials Made of non-sensitizing medical-grade materials Supports professional treatment-room use
Not made with natural rubber latex Electrodes are not manufactured with natural rubber latex Helps support latex-sensitive environments
Individual treatment pouches Each kit is individually packaged Simplifies treatment setup and storage

Treatment Setup Summary

Always follow the full IFU and the iontophoresis device manual. This summary is for education and should not replace the manufacturer instructions.

Step Setup Guidance
1 Read the iontophoresis device manual before treatment.
2 Use only with FDA-cleared, constant-current iontophoresis devices.
3 Remove one active drug electrode, one ground electrode, and one alcohol wipe from the pouch.
4 Clean both electrode placement sites thoroughly with the alcohol wipe.
5 Hydrate the drug delivery matrix with the required dosage.
6 Do not underfill or overfill the matrix.
7 Make sure no dry spots are visible before application.
8 Remove the liner and place the active electrode on the treatment area without compressing the drug matrix.
9 Place the ground electrode on a major muscle 4"–6" away from the active electrode.
10 Attach lead wires according to medication polarity.
11 Set the iontophoresis unit to the prescribed total charge and current level.
12 Turn the unit off before removing electrodes after treatment.

Fill Volume Guide

Electrode Option Required Matrix Hydration Volume
Small Square 1.5cc
Medium Square 2.5cc
Large Square 4.0 cc
Butterfly 2.0 cc

Important: Do not overfill or underfill the drug delivery matrix. Avoid dry spots. If dry spots are visible, lightly touch up the matrix with the syringe tip until the dry areas are gone.


Polarity Connection Guide

Connect lead wires according to the polarity of the drug or solution being delivered.

Drug / Polarity Drug Electrode Lead Ground Electrode Lead
Negative Black, negative Red, positive
Positive Red, positive Black, negative

Example Treatment-Time Table for 40 mA-Min

The IFU provides examples for delivering a recommended total charge of 40 mA-min.

Recommended Total Charge Current Time
40 mA-min 1 mA 40 minutes
40 mA-min 2 mA 20 minutes
40 mA-min 3 mA 13.5 minutes
40 mA-min 4 mA 10 minutes

Do not exceed an 80 mAmp·min dosage per single treatment. Current level and treatment time should follow professional direction, device instructions, patient comfort, and applicable prescribing guidance.


Ionto4™ vs. Wireless Iontophoresis Patches

Feature Ionto4™ Iontophoresis Electrodes Wireless Self-Powered Iontophoresis Patch
Power source External FDA-cleared constant-current iontophoresis device Built-in power source
Treatment control Controlled by the iontophoresis unit Controlled by the patch design
Kit contents Active electrode, ground electrode, alcohol wipe Patch or patch kit, depending on product
Size choices Small, Medium, Large, Butterfly Product-dependent
Medication included No No
Best for Clinics using constant-current iontophoresis devices Clinics wanting self-powered wearable patch workflow
Setup requirement Requires polarity and lead-wire connection Usually no external leads or controller

Ionto4™ vs. Reusable Electrotherapy Electrodes

Feature Ionto4™ Iontophoresis Electrodes Standard Reusable TENS/NMES Electrodes
Primary purpose Iontophoretic drug delivery Electrical stimulation contact
Single-use Yes Usually reusable
Drug matrix Yes No
Ground electrode included Yes Usually not paired as a drug/ground kit
Alcohol wipe included Yes Product-dependent
Medication delivery Designed for soluble salts or other medications under clinical direction Not designed for drug delivery
Device type Constant-current iontophoresis device TENS, NMES, EMS, or other electrotherapy device
Replacement decision Choose by matrix volume and placement Choose by size, shape, gel, and connector compatibility

Indications Summary

Ionto4™ Iontophoresis Electrodes are indicated for the administration of soluble salts or other medications into the body for medical purposes as an alternative to hypodermic injection.

Use should follow:

  • Prescriber direction

  • Medication labeling

  • Device instructions

  • Ionto4™ IFU

  • Facility protocol

  • Patient screening

  • Professional clinical judgment


Contraindications and Use Restrictions

Iontophoresis is contraindicated for patients with:

Contraindication / Restriction Explanation
Cardiac pacemakers or electrically sensitive implanted devices Electrical current may interfere with sensitive devices
Known sensitivity to the drug being administered Drug allergy or sensitivity must be considered before use
Known adverse reactions to electrical current Treatment may not be appropriate for patients with prior adverse responses.
Damaged skin or recent scar tissue Do not place electrodes over compromised skin
Temporal or orbital regions Do not use across the temporal regions or for treatment of the eye region

Key Warnings and Precautions

Ionto4™ electrodes should be used only according to the IFU, device manual, medication labeling, and professional guidance.

Warning / Precaution Practical Meaning
Use only with FDA-cleared constant-current iontophoresis devices Do not use with incompatible devices
Do not exceed 80 mAmp.min per single treatment Follow dosage limits
Single-use only Do not reuse after treatment
Do not apply over damaged skin Avoid open wounds, pimples, recent scar tissue, or recently healed tissue
Avoid hair follicles and moles Do not shave the application area immediately before use
Do not use over, weight-bearing areas Avoid pressure that can affect the patch during treatment
Do not bind, tape, or compress the electrode Pressure can affect performance and skin response
Do not get electrodes wet Moisture may cause electrodes to short
Do not allow metal contact Remove jewelry and keep metals away from electrodes
Do not remove electrodes before terminating current Turn off the current source before removing electrodes
Do not use drug suspensions Follow medication and solution requirements
Avoid gels, creams, or oils before treatment Do not apply to areas treated with gels, creams, or oils within the last 24 hours
Watch for irritation or burns Advise patients to report burning or discomfort immediately

Storage and Handling

Storage / Handling Item Guidance
Use type Single-use only
Sterility Non-sterile
Storage Store at room temperature
Heat exposure Do not expose to temperatures above 125°F / 50°C
Reuse Do not reuse after a single treatment
Disposal Discard after treatment according to facility policy

Product Description

The Ionto4™ Iontophoretic Delivery Kit is a dependable single-use electrode system for professional iontophoresis treatments. Each box includes 12 individually packaged kits, and each kit includes one active drug electrode, one return electrode, and one alcohol prep pad.

The active electrode is designed for optimized buffering and solution absorption, while the large ground electrode is designed to reduce sensation and improve patient comfort. The carbon-Ag/AgCl technology supports precise buffering, and the large adhesive surface area helps keep electrodes in place during treatment.

With four size options—Small Square, Medium Square, Large Square, and Butterfly—Ionto4™ gives clinicians flexibility when matching fill volume and electrode shape to the treatment site.

Order from Balego to source Ionto4™ iontophoresis electrodes, iontophoresis supplies, electrotherapy electrodes, contact media, and professional rehabilitation products from one trusted supplier.


What to Order With Ionto4™

Related Product Type Why It May Be Needed
FDA-cleared constant-current iontophoresis device Required to operate Ionto4™ electrodes
Medication or soluble salt solution Required for the prescribed treatment
Syringe or filling accessory Used to hydrate the drug delivery matrix
Gloves and clinical prep supplies Supports clean treatment setup
Skin prep supplies An alcohol prep pad is included, but facilities may need additional supplies
Electrode disposal supplies Supports single-use clinical disposal workflow
Iontophoresis documentation forms Helps record dose, current, time, site, and patient response

Buyer’s Guide

Choose Ionto4™ if

  • Your clinic already uses FDA-cleared constant-current iontophoresis equipment.

  • You need single-use drug-delivery electrode kits.

  • You want active and ground electrodes packaged together.

  • You prefer a kit that includes an alcohol prep pad.

  • You need multiple size and fill-volume options.

  • You want carbon-Ag/AgCl iontophoresis electrode technology.

  • You want electrodes not made with natural rubber latex.

  • Your facility prefers disposable treatment kits for consistent workflow.

Consider a self-powered patch instead if

  • You want a wireless patch with built-in power.

  • You do not want to connect lead wires to an external iontophoresis unit.

  • Your workflow is based around pre-designed mA-min patch delivery times.

  • You want patients to leave the clinic with a self-powered patch in place.


Why Buy Ionto4™ from Balego?

When you buy Ionto4™ iontophoresis electrodes from Balego, you can source professional iontophoresis products and clinical therapy supplies from a supplier focused on rehabilitation, electrotherapy, contact media, electrodes, and patient care products.

Balego offers:

  • Free shipping across the USA

  • Best-price guarantee

  • Professional therapy product selection

  • Iontophoresis product options

  • Electrotherapy and rehabilitation supply categories

  • Product support through our contact page


Frequently Asked Questions

What is Ionto4™?

Ionto4™ is a single-use iontophoresis electrode treatment kit used with FDA-cleared constant-current iontophoresis devices for professional drug-delivery iontophoresis workflows.

What comes in each Ionto4™ treatment pouch?

Each pouch contains one active drug electrode, one ground or return electrode, and one alcohol prep pad.

How many treatment kits come in a box?

Each box includes 12 individual treatment kits.

What sizes are available?

Ionto4™ is available in Small Square 1.5cc, Medium Square 2.5cc, Large Square 4.0cc, and Butterfly 2.0cc options.

Which SKU is the Small Square Ionto4™ electrode?

Small Square is SKU NC89375.

Which SKU is the Medium Square Ionto4™ electrode?

Medium Square is SKU NC89376.

Which SKU is the Large Square Ionto4™ electrode?

Large Square is SKU NC89377.

Which SKU is the Butterfly Ionto4™ electrode?

Butterfly is SKU NC89378.

Is Ionto4™ made with natural rubber latex?

No. Ionto4™ electrodes are not made with natural rubber latex.

Is Ionto4™ reusable?

No. Ionto4™ electrodes are single-use only and should be discarded after treatment.

Does Ionto4™ include medication?

No. Medication or solution is not included. Medication selection and use should follow prescriber direction, drug labeling, facility protocol, and the IFU.

What device is required?

Ionto4™ electrodes must be used with an FDA-cleared, constant-current iontophoresis device.

What is the maximum dosage per treatment?

Do not exceed an 80 mAmp·min dosage per single treatment.

How far away should the ground electrode be placed?

The IFU instructs users to place the ground electrode on a major muscle 4"–6" away from the active electrode.

How do I connect the polarity?

For a negative drug or solution, connect the drug electrode to black negative and the ground electrode to red positive. For a positive drug or solution, connect the drug electrode to red and positive and the ground electrode to black and negative.

Does Balego offer free shipping?

Yes. Balego lists free shipping across the USA for this product.

Does Balego offer a best-price guarantee?

Yes. Balego states that it will match competitor pricing when customers show a competing offer.



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Customer Reviews (5.0 / 5 · 5 reviews)

Miles F. ★★★★★

Finally, an electrode that doesn’t peel off mid-treatment. I used it for a full 30-minute iontophoresis session and the gel pads stayed moist the entire time.

Christopher N. ★★★★★

The adhesive stayed put even during a 20-minute treatment, which was my biggest worry. These single-use kits made setup much simpler than the reusable pads I tried before.

David A. ★★★★★

The current flows evenly through these, which made my plantar fasciitis treatments way more comfortable than the reusable pads I used before. Single-use is honestly nicer too, no cleanup between patients. Twelve per box lasts me about two weeks.